Brunhilde Wirth Selected Research

cyclic hexapeptide(Phe-Phe-Trp-Lys-Thr-Phe)- somatostatin (CHP1)

1/2019	PLS3 Overexpression Delays Ataxia in Chp1 Mutant Mice.
2/2018	Biallelic CHP1 mutation causes human autosomal recessive ataxia by impairing NHE1 function.
1/2018	CHP1 reduction ameliorates spinal muscular atrophy pathology by restoring calcineurin activity and endocytosis.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Brunhilde Wirth Research Topics

Disease

42	Spinal Muscular Atrophy (Progressive Muscular Atrophy) 01/2022 - 03/2006
9	Neurodegenerative Diseases (Neurodegenerative Disease) 11/2021 - 02/2008
5	Ataxia (Dyssynergia) 12/2021 - 01/2018
5	Motor Neuron Disease (Primary Lateral Sclerosis) 01/2020 - 02/2008
3	Neoplasms (Cancer) 07/2021 - 10/2009
3	Osteoporosis 07/2021 - 10/2013
2	Mitochondrial Diseases (Mitochondrial Disease) 12/2020 - 02/2007
2	Congenital Myasthenic Syndromes (Myasthenia Gravis, Congenital) 01/2017 - 02/2008
2	Parkinson Disease (Parkinson's Disease) 01/2014 - 02/2007
1	Bone Fractures (Bone Fracture) 07/2021
1	Cakut 01/2021
1	Albuminuria 01/2021
1	Nervous System Diseases (Neurological Disorders) 01/2020
1	Optic Atrophy 01/2020
1	Polyneuropathies (Polyneuropathy) 01/2020
1	Menkes Kinky Hair Syndrome (Menkes Disease) 10/2019
1	Occipital horn syndrome 10/2019
1	Atrophy 01/2019
1	Deafness (Deaf Mutism) 02/2018
1	Spinal Muscular Atrophies of Childhood (Werdnig Hoffman Disease) 01/2018
1	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2018
1	Spinal Diseases (Disease, Spinal) 10/2017
1	Muscular Atrophy (Muscle Atrophy) 10/2017
1	Alzheimer Disease (Alzheimer's Disease) 01/2014
1	Dementia (Dementias) 01/2014
1	Osteoporotic Fractures 10/2013
1	Infant Death 04/2013
1	Neuromuscular Diseases (Neuromuscular Disease) 04/2013
1	Type V Osteogenesis Imperfecta 08/2012
1	Adrenoleukodystrophy (Adrenoleukodystrophy, X-Linked) 05/2010
1	Respiratory Insufficiency (Respiratory Failure) 04/2010
1	Paralysis (Palsy) 04/2010
1	Disease Progression 01/2009
1	Rubinstein-Taybi Syndrome (Syndrome, Rubinstein-Taybi) 02/2008
1	Stroke (Strokes) 02/2008
1	Huntington Disease (Huntington's Disease) 02/2008
1	Multiple pterygium syndrome 02/2008
1	type 1 Pena Shokeir syndrome 02/2008
1	X-Linked Bulbo-Spinal Atrophy 02/2008

Drug/Important Bio-Agent (IBA)

25	Proteins (Proteins, Gene)FDA Link 11/2021 - 03/2006
8	plastinIBA 01/2021 - 04/2008
5	Histone Deacetylase InhibitorsIBA 06/2013 - 07/2006
3	nusinersenIBA 01/2022 - 01/2019
3	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2018
3	ADP-ribosylarginine hydrolaseIBA 12/2021 - 01/2018
3	Antisense OligonucleotidesIBA 01/2020 - 01/2018
3	cyclic hexapeptide(Phe-Phe-Trp-Lys-Thr-Phe)- somatostatin (CHP1)IBA 01/2019 - 01/2018
3	Actins (F Actin)IBA 12/2018 - 04/2013
3	UbiquitinIBA 10/2018 - 04/2014
3	Valproic Acid (Depakote)FDA LinkGeneric 01/2018 - 06/2006
3	Histone Deacetylases (Histone Deacetylase)IBA 01/2009 - 07/2006
2	CalcineurinIBA 01/2019 - 01/2018
2	NeurocalcinIBA 01/2019 - 01/2017
2	Golgi Matrix ProteinsIBA 01/2015 - 06/2013
2	Vorinostat FDA Link 08/2006 - 07/2006
1	Cathepsin DIBA 01/2022
1	podocalyxinIBA 01/2021
1	nephrinIBA 01/2021
1	ProteomeIBA 01/2021
1	SolutionsIBA 01/2021
1	Electron Transport Complex I (NADH-CoQ Reductase)IBA 12/2020
1	Vitamin B 6IBA 01/2020
1	Nucleic AcidsIBA 01/2020
1	Copper-Transporting ATPasesIBA 10/2019
1	CarboxypeptidasesIBA 01/2019
1	CalciumIBA 01/2019
1	EnzymesIBA 10/2018
1	MicroRNAs (MicroRNA)IBA 01/2018
1	Carnitine (L-Carnitine)FDA LinkGeneric 01/2018
1	LigandsIBA 10/2017
1	Metalloproteases (Metalloproteinases)IBA 10/2017
1	Vesicle-Associated Membrane Protein 1IBA 01/2017
1	HydrolasesIBA 12/2014
1	CateninsIBA 04/2014
1	DNA (Deoxyribonucleic Acid)IBA 02/2014
1	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 01/2014
1	quisinostatIBA 06/2013
1	Collagen Type I (Type I Collagen)IBA 08/2012
1	alpha2 Subunit Collagen Type IIBA 08/2012
1	Initiator Codon (Start Codon)IBA 08/2012
1	Profilins (Profilin)IBA 12/2011
1	rho-Associated KinasesIBA 12/2011
1	AntioxidantsIBA 05/2010
1	hexacosanoic acidIBA 05/2010
1	Hydroxamic Acids (Hydroxamic Acid)IBA 10/2009
1	PanobinostatIBA 10/2009
1	Messenger RNA (mRNA)IBA 03/2008
1	Cholinergic ReceptorsIBA 02/2008
1	Histones (Histone)IBA 02/2008
1	Glutathione (Reduced Glutathione)IBA 02/2007
1	RNA (Ribonucleic Acid)IBA 08/2006
1	benzamideIBA 08/2006
1	Pharmaceutical PreparationsIBA 07/2006
1	Amino Acids FDA Link 03/2006

Therapy/Procedure

9	Therapeutics 07/2021 - 06/2006
1	Bite Force (Occlusal Forces) 06/2020
1	Investigational Therapies (Experimental Therapy) 01/2015